Because of the shortage of tomato germplasm at present, the study and creation of germplasm are of great significance in tomato breeding. There are abundant genetic resources in wild species and those related wild species, all of them are valuable for the improvement of tomato genetic resources. Wide crossing have been the best to improve tomato genetic resources, but the incompatibility in wide crossing of tomato is a limiting factor to affect the result. The current studies on this area were reviewed in this paper.