The experiment was carried out to compare effect of five chemicals on controlling Holotrichia obeita in peanut field.Results showed that number of Holotrichia obeita in peanut field decreased by 91.40% and 82.51% 20 days of application of 48% Chlorpyrifos and 40% Bibensheng.The disease control effect was 95.66% and 87.11% and the yield of peanut increased by 45.09% and 33.72%.Effects were better than that of 40% Phoxim EC and 40% Isofenphos-methy.But effect of application of 10% Imidacloprid was the same as that of application of 48% Chlorpyrifos and 40% Benbisheng.