Abstract:To prevent Avian Influenza,comprehensive measures must be taken,for example,the immunization of vaccine,the usual test and quick diagnostic after falling ill,etc.It requests that rapid specific methods of diagnostic and test for the virus must be established and new types of vaccine developed continually.Baculovirus-insect cell expression system has successfully expressed about a thousand highly valued proteins,for it has perfect processing and decorating system after translation and the ability to express the external genes efficiently.The application of this system in Avian influenza virus laid a basis for producing specific antigen for preventing Avian Influenza,the discovery of diagnostic-test-method,and the development of new types of genetic engineering vaccine.