With compact variety ’Xianyu 335’ as tested material,effect of four herbicides on number of weeds and the dry weight of corn seedling leaves was studied.The results showed that with the reduction of the amount of herbicide application,the weed control effect decreased.Spraying the 2,4-D,acetochlor and atrazine mixture 5-7 days after sowing could control weeds in cornfield effectively.The proportion of them was 4:6:1 and the field application amount was 4.4 L/hm2.And spraying 0.6 L nicosulfuron and 0.96 L atrazine per hectare when weeds were 3-4 leaf could weeds in cornfield.