The yield of twelve maize varieties in cold-humid region of Jilin province was compared.The results showed that on flat land under accumulated temperature of 2 750℃the yield of ’Liangyu11’, ’Xianyu 335’, ’Jidan 550’ was 13 364.0 kg/hm², 13 217.7 kg/hm² and 12 726.7 kg/hm² respectively, which was extremely significant higher than that of the other five varieties.On slope land under accumulated temperature of 2 750℃, the yield of ’Liangyu 11’, ’Xianyu 335’ was 9 652.0 kg/hm² and 9 565.3 kg/ hm² respectively, which was extremely significant higher than that of the other five varieties.On flat land under accumulated temperature of 2 600℃, the yield of ’Jidan 27’, ’Ketai 199’ was 11 746.0 kg/hm² and 11645.0 kg/hm² respectively, which was extremely significant higher than that of the other two varieties.The suitable varieties for different plant area were screened in the experiment, which provide scientific basis for high yield, stable yield, high quality, efficient cultivation technique of maize in cold-humid region.