Through the inhibition of herbicide to the wheat bud,it was determined that the EC50 of nicosulfuron was 2.92mg/L and that of clomazone was 10.77mg/L.Mixture of different proportion of metrobizom and nicosulfuron displayed the adding effect.Among 5 mixtures,the adding effect of mass ratio 4:1 was obvious and the poisonous coefficient was the most greatly,141.The content of the mixture is 10%,among which 8% was metrobizom and 2% was nicosulfuron.