The study was on the extraction of natural pigment from Lonicera caerulea L. var. enulis Turcz et Herd by solvent extraction method. Factors influencing stability of natural pigment were analyzed. The factors of Ethanol concentration, temperature, time,and pH value were chosen in single-factor test and orthogonal experiment. Furthermore, factors which influenced natural pigment’s stability were analyzed, such as light, sucrose, reductant-oxidant and metal ion. The results showed that the optimum conditions of extraction were ethanol concentration 60%, temperature 60℃, time 60min, pH value of 2. As the amount of sucrose increased absorbance values were also gradually increased. The pigment’s stability was sensitive to reductant-oxidant. The effect of metal ions Fe³⁺, Ca²⁺, Cu²⁺ to the stability of pigment was not significant, but effect of Na⁺ was more significant.