Using resistant maize ‘BT-1’and sensitive maize ‘N6’as materials, O₂^·- production rate, MDA content, POD and SOD activity in maize seedlings were measured after induced by Fusarium moniliforme. The results showed that O₂^·- production rate and MDA content increased after inoculation, and they were higher in resistant cultivars higher in sensitive cultivars. The peak of O₂^·- production rate in resistant cultivars appeared early and high, which reached its maximum at 36 h, being 5.8 times of control. Changes of SOD activity were apparent in resistant cultivars and higher than sensitive cultivars. POD activity was increased after inoculation, but higher in sensitive cultivars than resistant cultivars. It was suggested that protective enzymes and active oxygen appeared apparent differences in resistant and sensitive cultivars after inoculation by Fusarium moniliforme, the changes may reflect the different regulatory mechanisms in resistant and sensitive maize induced by pathogen.