By comparing of soil nutrient condition with fertilization and no fertilization treatments, the effect of soil salinization and nutrient inputs on soil fertility of paddy field was clarified, which provides theoretical basis for formula fertilization in soda alkali-saline area. The results showed that the contents of total N, available N, total P, available P and available K in alkali-saline soil decreased with fertilization and no fertilization treatments. But change of total K content was different. It decreased in no fertilization treatments.In fertilization treatment, the content of total K increased. After chemical fertilizer was applied, the contents of total N, total P and available P were increased, respectively. However, available N decreased correspondingly.The contents of total K and available K were influenced by soil types and plant variety.