In this study, the encoded gene of transcription factor Os1137 was isolated from the cDNA of rice by PCR amplification. The gene was driven by Ubi promoter to construct plant expression vector p3300-Os1137, which was introduced into tobacco via agrobacterium-mediated transformation. The salt tolerance of the transgenic plant was analyzed by testing physiological changes of the transgenic tobacco plants under different salt stresses. Results showed that less increment of MDA contents and more of proline contents in the transgenic plants respectively in high salinity were obtained. Quantitative test showed that the salt tolerance of tobacco plants was improved by this gene expression.