It is of great significance to analysis limited factors of grain production capacity and predict produc-tion potential in Liaoning Province in order to ensure food security and promote economic and social harmonious de-velopment. Based on data of 1979-2010, factors limited grain production and yield were analyzed in the paper.Meanwhile, linear correlations between these factors were analyzed, and main and minor or latent influencing factorsfound. According to the statistical results, a detailed analysis of the main problems limited the lift of comprehensivegrain production capacity was done combined with the actual situation in Liaoning Province. By using linear regres-sion, principal factor stepwise regression and correlation analysis to deal with the historical data, stepwise regressionprediction model, logic model, Christian the power function model, Gauss model, Cubics prediction model for Ratioprediction model in Dps software were established to predict the grain yield and total production in the future.