Take the soil in Panax ginseng continuous cultivating field as research objects, the effects of differentmicrobial agents on soil enzymes were studied. The result showed: the soil activities in P. ginseng continuous culti-vating field increased with the increasing concentration of Prebiotics Cropping Agent, Hartz trichoderma Agent,"5406"Agent and Bacillus Agent, but the soil activities reduced with the higher concentration of the agents. Thesoil sucrase activities were higher when the Hartz trichoderma Agent of 5 g/m²（B1） and Bacillus Agent of 2 g/m²（D2）were used in the P. ginseng continuous cultivating field, which increased 76.07% and 65.91% compare withCK, respectively. In addition, the catalase and acid phosphatase activities were higher than others when the Hartz trichoderma Agent of 5 g/m² and"5406"Agent of 100 g/m²（C3） were used. Considering the soil activities, the Hartz trichoderma Agent of 5 g/m2（B1） is recommended in the P. ginseng continuous cultivating field in order to in-crease the soil activity.