Three kinds of herbicides and a compound agent was applied before emergence of Sorghum‘Chiza 28’and two kinds of herbicides and a compound agent was applied after emergence. Herbicides which had effectiveweed controlling and ensure a normal growth of‘Chiza 28’were selected by comparison and analysis of weed con-trol effect and yield of grains. The results showed that after sowing and before emergence, 129.2 m L of 72% ISO-Propylene compound and 323 m L 38% Atrazine per 667 m² can be used for closed spray, and after emergence andin 2~4 leaf stage 323 m L of 38% atrazine per 667 m² can be applied. The above two methods are safe for weed con-trolling of sorghum hybrid‘Chiza 28’.