During 2013 to 2014, for making clear the disease resistance of 54 maize hybrids from Guangxi seed mar-ket, artificial inoculation method was used to evaluate the resistance against corn sheath blight, southern leaf blightand southern rust. The results showed that among the 54 hybrids, 12 were resistant（including high resistant） tosheath blight, 27 were resistant（including high resistant） to southern leaf blight, 13 were resistant（including highresistant） to southern rust.‘Guidan 0810’,‘Guidan 589’and‘Zhengda 808’were resistant to all three kinds ofdiseases.‘Guidan 688’,‘Guidan 162’,‘Zhaofeng 588’and other 14 varieties were resistant to two diseases. It wasconcluded that although there were plenty of corn hybrids in Guangxi market, but few of them were resistant toall diseases. In order to avoid the risk of lose caused by diseases in maize production, hybrids resistance to morethan two kinds of maize diseases should be chosen.