In this study, the cDNA-AFLP technique was used to establish the gene expression profiles of rice infect-ed by Magnaporthe grisea, and the function of differential display expressed genes was analyzed. Nine hundred sixtytranscript derived fragments were obtained by using 64 pairs of primers. Two hundred fragments were recovered andsequenced, one hundred thirty four readable sequences were obtained. Seventy four non duplicated TDFs were got-ten by BLAST analysis. Among the statistical expression of 74 TDFs corresponding on PAGE, the number of up-reg-ulation genes was more than down-regulation genes after innoculated by Magnaporthe grisea, six were early up-reg-ulation genes, eleven were late up-regulation genes, thirty two were other forms of up-regulation genes, the totalnumber of down-regulation genes was 25.