Soil salinization is increasing and causes arable area reduction year by year. It has become a main limit-ing factor affecting the grain production in our country. At present, improving the salt tolerance of crop is urgentlyneeded for plant breeding. With the rapid development of modern molecular biology technology, Scientific research-ers have cloned a number of salt-tolerance related genes and some salt-tolerant transgenic rice have been obtained.In the paper, cloning of salt-tolerance related genes in plants and genetic transformation of rice have been summa-rized. The problems and prospect of their application in genetic transformation of rice in future were also discussed.