The influence of three herbicide applications in corn field to control efficiency（CE） and safety were evalu-ated in field. The results showed that the best CE was 2 times applications of post-emergency herbicides, the betterCE was one time application of post-emergency herbicides and the worst was the applications of pre-emergency her-bicides. The CE of fresh weight herbs were 99.1%, 89.2%-89.7% and 63.5% respectively. All of 3 applicationsmethods were safety to corn, and there was not any adverse effects to corn height, fresh weight and yields in 2 timesapplications of post-emergency herbicides. The yields were same with manual weeding and it was suitable to bewidespread.