Adlay as a edible medicine crop, has the reputation of the king of cereals. The inevitable course of agricultural development is agricultural industrialization. The development of agricultural industrialization in China showed imbalance. To meet the requirement of Adjustment of agricultural structure of Guizhou Province and requirement of adlay industry in Qianxi'nan of Guizhou Province, plan of adlay plantation was set up by the local governments. Special attention was payed to the development of the industrialization of adlay in Qianxi' nan of Guizhou Province, and support was given from different aspects for adlay development. Methods were adopted, such as market-driven, leading enterprises, the base drive, mutual assistance, etc. which greatly promoted the development of agriculture and rural economy in Qianxi'nan. Farmers of the local planting enthusiasm has been driven, which play an important role in alleviate poverty. Through analysis of advantage of natural conditions, advantage of adlay resources, requirement of market, economic benefits, layout and advantages of adlay in Qianxi'nan were summed up.Key problems of industrial development of adlay in this region were analyzed, which will provide theoretical support for industrial development of adlay in this region.