In this experiment, based on different nutrient solutions of water cultured cucumbers, different concentrations of Hogan’s nutrient solution（with 20%, 40%, 100%, 150%, and 200% dilution ratios） were used to hydroponics cucumber. After one cycle of cultivation, the effect of disinfection by the nutrient solution disinfection device and the growth of cucumber with hydroponics were measured. The results showed that the optimal disinfection conditions of the sterilization device for the remaining nutrient solution were: ultraviolet intensity of 30 W, nutrient solution concentration of 150%, and disinfection time of 200 s. The result has great significance for the recovery and utilization of nutrient residual liquid.