In this study, the polymorphism of growth hormone（pGH） in Large White Pigs was detected by HRM typing, and its correlation with growth traits was analyzed. A total of 246 large white pigs were collected as research objects. Ear tissues DNA was extracted using DNA extraction kit. After PCR amplification of samples from 20 pigs, the polymorphic sites of the gene in the population were searched by sequencing. HRM-specific primers were designed for the polymorphic sites found, and the HRM method was used to detect polymorphism in samples from 226 pigs,and the results were correlated with production data. The results showed that one mutation site 1856 C＞T, two alleles C and T, three genotypes CC, CT and TT were detected in the pGH gene sequence. The χ² suitability test showed that the genotype frequency and allele frequency of the gene were not significantly different among the small populations, which was consistent with the Hardy-Weinberg equilibrium law（P＞0.05）, but the genotype frequency of the gene in the large population. The frequency distribution of the alleles was significantly different and did not conform to the Hardy-Weinberg equilibrium law（P＜0.05）. According to polymorphic information content（PIC） analysis, the pGH gene was in low polymorphism（PIC＜0.25） in small populations, but moderate polymorphism（0.25＜PIC＜0.5） in large populations. In the association analysis with growth traits, the pGH gene had a significant effect on the weight of 20 days and the weight of the two months（P＜0.05）. In summary, the pGH gene has a certain influence on the growth and development of Large White Pigs. This will provide reference for the modern molecular breeding of the subsequent white pork quality traits and growth traits.