Naked oats is one of the characteristics crops in Inner Mongolia. It has such physiological functions as lower blood sugar and blood lipid. In order to extract the polyphenols of naked oats to the maximum extent, this study was conducted with enzyme-microwave assisted extraction of phenolic compounds from naked oats. On the basis of polyphenols yields, naked oats was pretreated by compound enzyme firstly, then single factor and orthogonal experiments were conducted to determine the optimum extraction technology of oats polyphenol. The results showed that when 0.8% compound enzyme dosage, enzymolysis time 80 min, enzymolysis temperature 55℃, pH 5.0 was used, the best extraction conditions were: 80% of ethanol, extract temperature 60℃, microwave power 700 W, phenolics extraction yield 2.01 mg/g. Also, when compared with the enzyme and microwave extraction method, the enzyme-microwave extraction method can improve 42% and 85% yield of phenolic compounds, respectively. It suggested that enzyme-microwave extraction process is an effective method to extract polyphenols of oats.