In order to formulate the drip irrigation and fertilization scheme for orchard in Gannan area, two-year field experiments of drip irrigation for pomelo were conducted. The effects of soil moisture distribution under different water treatments on the growth and quality of pomelo were studied. The results showed that soil water content showed the change rule of D treatment > C treatment > B treatment > A treatment. The larger the irrigation water content, the higher the soil moisture and the more water stored in soil. When the soil water content was 0.15 cm3/cm3 in pomelo growth period, the sprouting rate of pomelo shoots, the growth rate of new shoots and the fruit growth were the largest and the fruit quality was the best. The soil moisturewas controlled at 0.15 cm3/cm3 and the ratio of fertilizer application in the whole growth period was N-P2O5-K2O∶1-0.6-0.8 kg/(plant-year) during the growth period of pomelo in Gannan. This drip irrigation and fertilization method is a better irrigation fertilization scheme for pomelo in Gannan orchard, and can be used in agricultural production practice.