In order to investigate the difference between the grain quality and toxin pollution among spring wheat cultivars,a comparative analysis was made on the difference between the quality,physical characteristics and toxin pollution of 11 spring wheat cultivars planted in the Inner Mongolia Hulunbeier League in 2017. The results showed that there were significant differences in physical characteristics and nutritional quality between varieties（P＜ 0.05）.Some species were detected with biotoxin,which was mainly concentrated in DON and ZEN. But none exceeded the national limit standard, which showed that the risk of biotoxin pollution of spring wheat in North China was low and the quality safety level was relatively high. According to the analysis of physical characteristics and nutritional indexes, compared with the general level of wheat in China, northern spring wheat has the advantages of plump grain,low incomplete grain rate and impurity rate, high protein content, and is suitable for processing flour for baking.