Soil salinization is the main abiotic stress affecting agricultural production in China, which seriously affect crop growth and leading to yield reduction. In this study, two representative pepper varieties "Peasant Hot Girl"（high pungency degree） and "Super Sweet Pepper King"（low pungency degree） were selected as experimental materials to analyze plant height, stem diameter, peroxidase（POD） activity, soluble sugar content and soluble protein content of pepper varieties with different pungency degree under low, medium and high sodium salt stress. The results showed that the plant height, stem diameter, POD activity and osmotic regulators（soluble sugar and soluble protein）content in "Peasant Hot Girl" were increased under low and moderate sodium stress, while the "Super Sweet Pepper King" with low and medium sodium stress was inhibited in varying degrees. Therefore, the "Peasant Hot Girl" have better salt tolerance, can withstand low and medium sodium salt stress, and the "Super Sweet Pepper King" is not salt-tolerant. In addition, POD, soluble sugar and soluble protein can be used as response indicators of stress resistance to sodium salt stress in pepper with different degrees of hot pepper, providing identification reference and theoretical basis for breeding new varieties of pepper resistant to sodium salt stress.