Using Reka blueberry variety as test material, the fruit branches were dipped with different concentrations of GA₃, CPPU before and after anthesis to study the effect of Reka on fruit physiology of blueberry. Compared with the control, 100 mg/L 100 mg/L GA₃ could advance blueberry flowering by 3 days and 75 mg/L GA₃ could increase fruit setting rate by 8.9%. 10 mg/L CPPU could increase anthocyanin content by 12.7%. The results showed that high concentration of GA₃ could advance the flowering period, increase the fruit setting rate and increase the sugar content in the fruit. Low concentration of CPPU could significantly increase the contents of titratable acid, vitamin C and anthocyanin in fruit. The optimal concentration of GA₃ was 75 mg/L, and the concentration of CPPU was 10 mg/L. Under this concentration, the comprehensive quality of fruit growth of blueberry was the best.