In order to study the impact of climate change on major crops in Jiangxi Province, this paper analyzed climate change in Jiangxi Province, yield changes of six major crops and the impact of climate factors on yield per unit area of crops by using Mann_Kendall test, H-P filter and multiple regression method based on the relevant data of Jiangxi Province from 1988 to 2018. The results showed that: The temperature rise has a significant positive effect on the yield per unit area of main crops in Jiangxi Province. Rice and oil crops have the least fluctuation in the impact of climate change. Wheat, corn and potato are subject to great fluctuations due to climate change. It is suggested that Jiangxi Province maintain the existing crop planting structure and improve field management techniques to cope with the hazards of climate change.