In order to screen out efficient and safe herbicides for sorghum after emergence, this study evaluated the safety of 12 herbicides used in sorghum field. The results showed that 7 herbicides, such as mesotrione and Clodinafop acid, were harmful to sorghum, while 5 herbicides, such as atrazine and quinclorac, had little effect on the growth of sorghum. The safe dosage of these 5 herbicides in sorghum field was determined.