In order to clarify the chemical composition and availability of flue-cured tobacco in Baise City.Chemical composition characteristics of 275 flue-cured tobacco samples from 5 grades of B₂F,B₃F,C₂F,C₃F and X₂F in 11typical towns of Baise City were analyzed,and their usability was evaluated by fuzzy mathematics.The results showed that Baise City flue-cured tobacco had high total sugar and reducing sugar content,low nitrogen-base ratio,and other indicators were suitable.The chemical composition availability index of different grades was:C₂F＞C₃F＞B₂F＞B₃F＞X₂F.The chemical composition of B₂F and C₂F tobacco leaves is the highest in Longlin County,B₃F is the highest in Jingxi County,C₃F and X₂F are the highest in Debao County,and the average chemical availability index of flue-cured tobacco in Baise City is between 75.47 and 82.43,which is ’better’ grade.The chemical composition availability index of flue-cured tobacco has a downward trend from the middle to the north.Generally,it is higher in Debao County,followed by Longlin County and Jingxi County.