Toxicities of 8 fungicides were determined according to the inhibitory rates of the blast fungi mycelia growth in media containing the fungicides, and the control efficiency of the fungicides were evaluated by greenhouse test. The results showed that prochloraz was the most effective against the mycelial growth with the EC₅₀value of0.692 mg/L. The EC₅₀values of fenoxanil, carbendazim, trifloxystrobin·tebuconazole and copper sulfate basic were less than 3.0 mg/L, showing strong inhibitory effect. The EC₉₀of carbendazim was 1.929 mg/L and was the lowest.Prochloraz, fenoxanil, carbendazim and trifloxystrobin·tebuconazole showed the obviously protective effect on rice leaf blast, which were 73.3%-76.4%, respectively. The experiment provides suggestion for screening effective fungicides and controlling rice blast in northeast China.