To improve the high-yield cultivation techniques of the new sorghum variety Jiza 375 and provide theoretical basis for its planting and promotion. This experiment used Jiza 375 as the experimental material, and set different planting densities（100,000, 110,000, 120,000, 130,000 plants/ha） and fertilization methods（base fertilizer plus nitrogen fertilizer, slow-release long-term compound fertilizer） to screen the optimal planting density and fertilization method for Jiza 375. The results showed that the yield of Jiza 375 showed an upward trend within the density range from 100,000 to 130,000 plants/ha. Under the fertilization method of adding base fertilizer and nitrogen fertilizer, within a certain range, the yield increases with the increase of nitrogen fertilizer. In this experiment, the optimal planting density for Jiza 375 is 130,000 plants/ha, and the optimal fertilization method is compound fertilizer +nitrogen fertilizer 15 kg/666.7 m² and slow-release long-term compound fertilizer 40 kg/666.7 m².