In order to regulate the conversion of fertilizer nutrients in the soil and reduce nutrient losses, this study conducted a two-year corn field location trial in Lishu County, Jilin Province, to systematically study the application effects of efficiency N fertilizers with humic acid, alginate, amino acids and conditioners, and to screen out the optimal application formulations, with a view to providing a feasible way to reduce weight and increase efficiency in corn production. The results of the comprehensive two-year positioning test showed that the efficiency nitrogen fertilizer significantly improved the corn yield and fertilizer utilization. Compared with common urea treatment, maize yield increased by 7.17%, 5.43%, 5.52% and 3.41% with N fertilizer synergist Ⅰ、Ⅱ、Ⅲ and Ⅳ, respectively. N fertilizer utilization increased by 12.72%, 2.68%, 2.71% and 5.42%, respectively, and agronomical efficiency increased by 5.24, 4.29, 4.41, 1.82 kg/kg, respectively. The maize yield increase, nitrogen fertilizer utilization rate and agronomic efficiency increased the most and had the best effect with the retroactive application of efficiency-enhancing nitrogen fertilizer type I, which is the most suitable type of nitrogen fertilizer for maize cultivation in this region.