A two-year fixed plot experiment was conducted in the major maize production area in Henan Province, 6 controlled release nitrogen fertilizer (CRN) with conventional nitrogen fertilizer (N) treatments were arranged, including T₁(100%N), T₂(25%CRN+75%N), T₃ (50%CRN+50%N), T₄ (75%CRN+25%N), T₅ (100%CRN), and CK (no nitrogen fertilizer), effects of CRN combined with N on nitrogen accumulation, nitrogen use efficiency and yield of continuous summer maize. The results showed that the combination of CRN and N increased significantly grain yield, dry matter and nitrogen accumulation, and fertilizer use efficiency of summer maize, compared with single basal application of conventional nitrogen fertilizer, which were increased firstly and then gradually decreased with the increase of proportion of CRN. The nitrogen accumulation increased by 4.5%-11.2% and 4.5%-15.6% in the maturity stage, respectively, dry matter accumulation increased by 2.8%-17.6% and 9.5%-18.6%, respectively, from 2019 to 2020. The treatment T₃ and T₄ improved the agronomic efficiency, apparent benefit efficiency, partial productivity a harvest index of nitrogen fertilizer. The grain yield of the controlled release nitrogen fertilizer combined with conventional nitrogen fertilizer increased by 4.4%-12.2% and 5.4%-13.9%, respectively, the economic benefits increased 1-1 496 yuan/ha and 157-2 111 yuan/ha, respectively, compared with single basal application of conventional nitrogen fertilizer in 2019 and 2020. combined application of 75% CRN and 25% N could promote synergistic improvement of nitrogen use efficiency and yield in the treatment of nitrogen fertilizer level 225 kg/ha.