Through Introducing present situation of PGMSR study and its prefomance in the cold region, the value of its use and existing problem of PGMSR in the cold region were illuminated, and the main points of view how PGMSR were used in rice breeding were shown: (1) Defined a suitable breeding aim. Superior varieties with high resistance were crossed and WCVs were used as bridge of cross. (2) Multiple cross with continuous selection and the cyclic selection may be effective when new PGMSR is developed. (3) Because PGMSR could not be produced in the cold region, chemical control technique should be studied. It is suggested that stertile expression can be controlled with chemical method and PGMSR seed was produced in long sunshine.