The problem of antibiotic residue pollution has attracted widespread attention and high priority from researchers. Composting is an environmentally friendly method for solid organic waste disposal, which can effectively degrade antibiotics in the composting system and thus serves as a green disposal technology. This paper reviews the research progress in antibiotic degradation during solid waste composting at home and abroad, summarizes the degradation pathways of antibiotics in the environment, factors influencing antibiotic degradation during composting, and the degradation processes of antibiotics in environmental systems. Finally, future development trends in this field are prospected.